Synthesis of unnatural α-amino esters using ethyl nitroacetate and condensation or cycloaddition reactions

• Glwadys Gagnot,
• Vincent Hervin,
• Eloi P. Coutant,
• Sarah Desmons,
• Racha Baatallah,
• Victor Monnot and
• Yves L. Janin

Beilstein J. Org. Chem. 2018, 14, 2846–2852, doi:10.3762/bjoc.14.263

• -amino esters was achieved using gold(I) chemistry. Keywords: α-amino ester; α-nitro esters; cerium ammonium nitrate; cycloaddition; gold(I) cyclization; Introduction In the course of our work on an original synthesis of imidazo[1,2-a]pyrazin-3(7H)-one luciferins [1], a large variety of racemic α-amino